K-ras point mutations in routinely processed tissues: non-radioactive screening by single strand conformational polymorphism analysis.
نویسندگان
چکیده
منابع مشابه
K-ras point mutations in routinely processed tissues: non-radioactive screening by single strand conformational polymorphism analysis.
AIMS To develop a non-radioactive method to screen routinely fixed, paraffin wax embedded specimens for the occurrence of point mutations; to evaluate the single strand conformational polymorphism (SSCP) analysis technique for the detection of K-ras point mutations as a result of electrophoretic mobility shifts. METHODS DNA was extracted from archival specimens of colon cancer and from establ...
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ژورنال
عنوان ژورنال: Journal of Clinical Pathology
سال: 1993
ISSN: 0021-9746
DOI: 10.1136/jcp.46.7.621